Summary: A medical mystery that was solved in the Hub; one family's efforts may help develop treatments for dementia and Alzheimer's disease.

Summary: Ted Reinstein reports on the new Boston, one that has room for four penthouses on the market asking for more than 30-million dollars.

Summary: Anthony Everett reports on the game changing work begun by the group Stand With Everyone Against Rape, and he tells us how our own Heather Unruh, along with her family, is part of this important effort.

Summary: A training ground for novice sailors, a roadside dragon, a place to escape the rat race and a working farm that's always looking for helping hands. A couple of spots to eat that you might want to check out.

Summary: A lunch break that nourishes the soul as well as the body, a pop-up class in stand-up comedy, a new bookstore from ``Wimpy Kid'' author Jeff Kinney, and a massive fitness center. Inside the jammed aisles of the new Boston Public Market.

Summary: Messy means good eating. That’s what Shayna Seymour learned in Cambridge at a Harvard Square noodle shop, Santouka. A Brookline restaurant known for its Middle Eastern cuisine is putting its falafel on a food truck and taking it on the road, while a legendary donut maker is bringing its creations to the Financial District (who wants a dowich?). Plus, Shayna discovers unusual bagel flavors in Cambridge, and a guided wine tour in Boston. And, because we’re still hungry, we check out a burger spot and a French bakery.

Summary: It’s been home to a city dump, a prisoner of war camp, and a trouble plagued housing project. But now Boston’s Columbia Point neighborhood is something else entirely - a destination … for students looking to get a world class education, for lovers of waterfront views, for amateur historians and would-be Senators. Tonight we’ll see how the combined draw of The John F. Kennedy Library, The Edward M. Kennedy Institute and The Commonwealth Museum has put this Point on the map for visitors.

Summary: Tonight Chronicle puts a human face on the Massachusetts opioid epidemic, traveling to local communities where drug abuse is taking a tragic toll. We’ll meet a twenty one year old girl from a well to do Boston suburb whose high school drinking progressed to prescription drug abuse and then heroin, and learn the sad story of a high school athlete whose sports injury led him to a fatal drug habit. We also visit an innovative recovery program inside the Middlesex House of Corrections, and travel to Plymouth where a unique drug court is a last chance lifesaver for many desperate people. Plus, we go to members of Governor Baker’s task force to learn how state and local officials are searching for solutions to the crisis.

Summary: Herb Chambers, Karen Kaplan, John Fish, Linda Pizzuti Henry - they are leaders in the worlds of business, media and the arts. And they’ve learned a few things along the way to the top. Tonight they share those lessons with Anthony, Shayna and Ted.

Summary: You might call it sweating for a cause. The latest trend in charitable fundraising has taken on an athletic tone, from amateur boxers entering the ring to support cancer research in Haymakers for Hope, to women playing football in the annual Blondes vs. Brunettes game sponsored by the Alzheimer’s Association. Also, a small army of charitable organizations and Boston businesses put together a “Style with Heart” makeover to ift the spirits of a woman with cancer. Plus, we learn how one nonprofit is introducing the sport of lacrosse to city kids.

Summary: Hanover Street in Boston's North End is still the heart of the city's Little Italy; Frank DePasquale serves up his own feasts at Bricco and Mare; a politically incorrect tour of the neighborhood; an espresso and a haircut at the Boston Barber.

Summary: Converse is transforming its iconic Chuck Taylor sneaker; a store that sells footwear for vegans (no leather, please); how MIT is making a name in the fashion world; JC checks out the shoe habits of some of her colleagues.

Summary: Tom Reilly received a dire diagnosis - he had an aggressive form of melanoma that was almost always fatal. Matthew Zwahlen’s mom and dad got the news no parents are prepared to hear - their toddler had developed neuroblastoma, an often deadly form of cancer. But there was good news for both patients as well - a new type of treatment might help. Tonight Heather Unruh reports on the breakthrough promise of immunotherapy that’s giving new hope to patients and their families.

Summary: Massachusetts spends millions on mosquito control. Yet, the state spends nothing on tick control, despite C.D.C. estimates of nearly 30,000 tick-borne illnesses per year in Massachusetts. What to do? Tonight, Anthony Everett has experts’ advice protecting your property, yourself and your family. He also travels to Cape Cod, home to the area’s first wellness center devoted to Lyme disease. And, Anthony’s on the job with Dan Wolff, who fights the tick problem with bows and arrows. Wolff is hired by homeowners to eliminate local deer, common hosts for ticks.